/* Reset and Base Styles */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

:root {
    --primary-color: #2563eb;
    --primary-dark: #1d4ed8;
    --secondary-color: #64748b;
    --accent-color: #06b6d4;
    --text-primary: #1e293b;
    --text-secondary: #64748b;
    --bg-primary: #ffffff;
    --bg-secondary: #f8fafc;
    --bg-accent: #f1f5f9;
    --border-color: #e2e8f0;
    --shadow-sm: 0 1px 2px 0 rgb(0 0 0 / 0.05);
    --shadow-md: 0 4px 6px -1px rgb(0 0 0 / 0.1), 0 2px 4px -2px rgb(0 0 0 / 0.1);
    --shadow-lg: 0 10px 15px -3px rgb(0 0 0 / 0.1), 0 4px 6px -4px rgb(0 0 0 / 0.1);
    --shadow-xl: 0 20px 25px -5px rgb(0 0 0 / 0.1), 0 8px 10px -6px rgb(0 0 0 / 0.1);
}

body {
    font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
    line-height: 1.6;
    color: var(--text-primary);
    background-color: var(--bg-primary);
}

.container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 0 1rem;
}

/* Header Styles */
.header {
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    background: rgba(255, 255, 255, 0.95);
    backdrop-filter: blur(10px);
    border-bottom: 1px solid var(--border-color);
    z-index: 1000;
    transition: all 0.3s ease;
}

.nav {
    display: flex;
    justify-content: space-between;
    align-items: center;
    padding: 1rem 2rem;
    max-width: 1200px;
    margin: 0 auto;
}

.nav-brand h1 {
    font-size: 1.5rem;
    font-weight: 700;
    color: var(--primary-color);
}

.nav-menu {
    display: flex;
    list-style: none;
    gap: 2rem;
}

.nav-link {
    text-decoration: none;
    color: var(--text-primary);
    font-weight: 500;
    transition: color 0.3s ease;
    position: relative;
}

.nav-link:hover {
    color: var(--primary-color);
}

.nav-link::after {
    content: '';
    position: absolute;
    bottom: -5px;
    left: 0;
    width: 0;
    height: 2px;
    background: var(--primary-color);
    transition: width 0.3s ease;
}

.nav-link:hover::after {
    width: 100%;
}

.hamburger {
    display: none;
    flex-direction: column;
    cursor: pointer;
}

.hamburger span {
    width: 25px;
    height: 3px;
    background: var(--text-primary);
    margin: 3px 0;
    transition: 0.3s;
}

/* Hero Section */
.hero {
    min-height: 100vh;
    display: flex;
    align-items: center;
    background: linear-gradient(135deg, var(--bg-secondary) 0%, var(--bg-accent) 100%);
    padding: 6rem 2rem 2rem;
    position: relative;
    overflow: hidden;
}

.hero-content {
    max-width: 1200px;
    margin: 0 auto;
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 4rem;
    align-items: center;
}

.hero-title {
    font-size: 3rem;
    font-weight: 600;
    line-height: 1.1;
    margin-bottom: 1.5rem;
    background: linear-gradient(135deg, var(--primary-color) 0%, var(--accent-color) 100%);
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    background-clip: text;
}

.hero-subtitle {
    font-size: 1.25rem;
    color: var(--text-secondary);
    margin-bottom: 2rem;
    line-height: 1.7;
}

.hero-buttons {
    display: flex;
    gap: 1rem;
}

.btn {
    padding: 0.75rem 2rem;
    border: none;
    border-radius: 0.5rem;
    font-weight: 600;
    text-decoration: none;
    display: inline-block;
    transition: all 0.3s ease;
    cursor: pointer;
    font-size: 1rem;
}

.btn-primary {
    background: var(--primary-color);
    color: white;
}

.btn-primary:hover {
    background: var(--primary-dark);
    transform: translateY(-2px);
    box-shadow: var(--shadow-lg);
}

.btn-secondary {
    background: transparent;
    color: var(--primary-color);
    border: 2px solid var(--primary-color);
}

.btn-secondary:hover {
    background: var(--primary-color);
    color: white;
    transform: translateY(-2px);
}

/* Neural Network Animation */
.hero-image {
    position: relative;
    height: 400px;
    display: flex;
    align-items: center;
    justify-content: center;
}

.neural-network {
    position: relative;
    width: 300px;
    height: 300px;
}

.neuron {
    position: absolute;
    width: 20px;
    height: 20px;
    background: var(--primary-color);
    border-radius: 50%;
    animation: pulse 2s infinite;
}

.neuron:nth-child(1) {
    top: 20%;
    left: 20%;
    animation-delay: 0s;
}

.neuron:nth-child(2) {
    top: 20%;
    right: 20%;
    animation-delay: 0.5s;
}

.neuron:nth-child(3) {
    bottom: 20%;
    left: 20%;
    animation-delay: 1s;
}

.neuron:nth-child(4) {
    bottom: 20%;
    right: 20%;
    animation-delay: 1.5s;
}

.connection {
    position: absolute;
    top: 50%;
    left: 50%;
    width: 200px;
    height: 2px;
    background: linear-gradient(90deg, transparent, var(--accent-color), transparent);
    transform: translate(-50%, -50%);
    animation: flow 3s infinite;
}

@keyframes pulse {

    0%,
    100% {
        transform: scale(1);
        opacity: 1;
    }

    50% {
        transform: scale(1.5);
        opacity: 0.7;
    }
}

@keyframes flow {
    0% {
        transform: translate(-50%, -50%) rotate(0deg);
    }

    100% {
        transform: translate(-50%, -50%) rotate(360deg);
    }
}

/* Section Styles */
.section-title {
    font-size: 2.5rem;
    font-weight: 700;
    text-align: center;
    margin-bottom: 3rem;
    color: var(--text-primary);
}

/*Recent lab news section */
.news {
    padding: 5rem 0;
    background: var(--bg-primary);
}

.news-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 2rem;
    align-items: center;
    justify-content: center;
    background: var(--bg-secondary);
    border-radius: 1rem;
    box-shadow: var(--shadow-md);
    padding: 2rem;
    margin: 0 auto;
    max-width: 1200px;
}

.news-list {
    list-style: none;
    margin: 0 left;
    padding: 0 20px;
}

.news-item {
    display: flex;
    gap: 2rem;
    flex-wrap: wrap;
    align-items: flex-start;
    background-color: #fff;
    padding: 20px;
    margin-bottom: 20px;
    border-radius: 8px;
    box-shadow: 0 2px 4px rgba(0, 0, 0, 0.1);
}

.news-card {
    display: flex;
    align-items: flex-start;
    gap: 16px;
    background: white;
    padding: 2rem;
    border-radius: 1rem;
}

.news-image {
    width: 300px;
    height: 200px;
    object-fit: cover;
    border-radius: 4px;
    margin-right: 20px;
}


.news-card a {
    display: inline-block;
    margin-top: 1rem;
    color: var(--primary-color);
    text-decoration: none;
    font-weight: 600;
}

.news-content {
    flex: 1;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
}

.news-content .news-title {
    font-size: 35px;
    font-weight: bold;
    margin-bottom: 10px;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
}

.news-content .news-time {
    color: #888;
    font-size: 14px;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
}

.morenews {
    text-align: center;
    margin-top: 2rem;
    color: var(--primary-color);
}

@media (max-width: 768px) {
    .news-card {
        width: 100%;
        display: flex;
        flex-direction: column;
        align-items: center;
        justify-content: center;
    }
    .news-image {
        width: 100%;
        height: auto;
        justify-content: center;
    }
}

@media (min-width: 768px) {
    .news-card {
        width: 100%;
    }
}



/* Research Section */
.research {
    padding: 5rem 0;
    background: var(--bg-primary);
}

.research-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 2rem;
}

.research-card {
    background: white;
    padding: 2rem;
    border-radius: 1rem;
    box-shadow: var(--shadow-md);
    text-align: center;
    transition: all 0.3s ease;
    border: 1px solid var(--border-color);
}

.research-card:hover {
    transform: translateY(-5px);
    box-shadow: var(--shadow-xl);
}

.research-icon {
    font-size: 3rem;
    margin-bottom: 1rem;
}

.research-card h3 {
    font-size: 1.5rem;
    font-weight: 600;
    margin-bottom: 1rem;
    color: var(--text-primary);
}

.research-card p {
    color: var(--text-secondary);
    line-height: 1.6;
}

/* About Section */
.about {
    padding: 5rem 0;
    background: var(--bg-secondary);
}

.about-content {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 4rem;
    align-items: center;
}

.about-text h2 {
    font-size: 2.5rem;
    font-weight: 700;
    margin-bottom: 1.5rem;
    color: var(--text-primary);
}

.about-text p {
    font-size: 1.1rem;
    color: var(--text-secondary);
    margin-bottom: 1.5rem;
    line-height: 1.7;
}

.lab-features {
    margin-top: 2rem;
}

.feature {
    margin-bottom: 1.5rem;
}

.feature h4 {
    font-size: 1.1rem;
    font-weight: 600;
    color: var(--text-primary);
    margin-bottom: 0.5rem;
}

.feature p {
    color: var(--text-secondary);
    margin: 0;
}

.about-image {
    position: relative;
    height: 300px;
    display: flex;
    align-items: center;
    justify-content: center;
}

.lab-visualization {
    position: relative;
    width: 250px;
    height: 250px;
}

.microscope {
    position: absolute;
    top: 20%;
    left: 50%;
    transform: translateX(-50%);
    width: 80px;
    height: 120px;
    background: linear-gradient(135deg, var(--primary-color), var(--accent-color));
    border-radius: 10px;
    animation: float 3s ease-in-out infinite;
}

.brain-sample {
    position: absolute;
    bottom: 20%;
    left: 50%;
    transform: translateX(-50%);
    width: 60px;
    height: 60px;
    background: var(--accent-color);
    border-radius: 50% 30% 50% 30%;
    animation: pulse 2s infinite;
}

@keyframes float {

    0%,
    100% {
        transform: translateX(-50%) translateY(0px);
    }

    50% {
        transform: translateX(-50%) translateY(-10px);
    }
}

/* Team Section */
.team {
    padding: 5rem 0;
    background: var(--bg-primary);
}

.team-grid {
    display: flex;
    align-items: center;
    flex-direction: column;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: 2rem;
}

.team-list {
    list-style: none;
    margin: 0 auto;
    padding: 0 20px;
    max-width: 1200px;
    display: flex;
    flex-direction: row;
    gap: 20px;
    flex-wrap: wrap;
    margin-bottom: 16px;
}

.image {
    width: 300px;
    border-radius: 4px;
    flex: 1;
}



/* Publications Section */
.publications {
    padding: 5rem 0;
    background: var(--bg-secondary);
}

.publications-list {
    max-width: 800px;
    margin: 0 auto;
}

.publication-item {
    background: white;
    padding: 2rem;
    border-radius: 1rem;
    margin-bottom: 1.5rem;
    box-shadow: var(--shadow-md);
    transition: all 0.3s ease;
}

.publication-item:hover {
    transform: translateY(-2px);
    box-shadow: var(--shadow-lg);
}

.publication-item h3 {
    font-size: 1.3rem;
    font-weight: 600;
    margin-bottom: 0.5rem;
    color: var(--text-primary);
}

.publication-journal {
    color: var(--primary-color);
    font-weight: 500;
    margin-bottom: 0.5rem;
}

.publication-summary {
    color: var(--text-secondary);
    line-height: 1.6;
}

/* Contact Section */
.contact {
    padding: 5rem 0;
    background: var(--bg-primary);
}

.contact-content {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 4rem;
    max-width: 1000px;
    margin: 0 auto;
}

.contact-info h3 {
    font-size: 2rem;
    font-weight: 700;
    margin-bottom: 1rem;
    color: var(--text-primary);
}

.contact-info p {
    font-size: 1.1rem;
    color: var(--text-secondary);
    margin-bottom: 2rem;
    line-height: 1.7;
}

.contact-item {
    margin-bottom: 1.5rem;
}

.contact-item h4 {
    font-size: 1.1rem;
    font-weight: 600;
    color: var(--text-primary);
    margin-bottom: 0.5rem;
}

.contact-item p {
    color: var(--text-secondary);
    margin: 0;
}

.contact-form {
    background: var(--bg-secondary);
    padding: 2rem;
    border-radius: 1rem;
}

.form-group {
    margin-bottom: 1.5rem;
}

.form-group input,
.form-group textarea {
    width: 100%;
    padding: 1rem;
    border: 1px solid var(--border-color);
    border-radius: 0.5rem;
    font-size: 1rem;
    transition: all 0.3s ease;
    background: white;
}

.form-group input:focus,
.form-group textarea:focus {
    outline: none;
    border-color: var(--primary-color);
    box-shadow: 0 0 0 3px rgba(37, 99, 235, 0.1);
}

.form-group textarea {
    resize: vertical;
    min-height: 120px;
}

/* Newsletter Section */
.newsletter {
    padding: 4rem 0;
    background: linear-gradient(135deg, var(--primary-color), var(--accent-color));
    color: white;
}

.newsletter-content {
    text-align: center;
    max-width: 600px;
    margin: 0 auto;
}

.newsletter h2 {
    font-size: 2.5rem;
    font-weight: 700;
    margin-bottom: 1rem;
}

.newsletter p {
    font-size: 1.1rem;
    margin-bottom: 2rem;
    opacity: 0.9;
}

.newsletter-form {
    display: flex;
    gap: 1rem;
    max-width: 400px;
    margin: 0 auto;
}

.newsletter-form input {
    flex: 1;
    padding: 1rem;
    border: none;
    border-radius: 0.5rem;
    font-size: 1rem;
}

.newsletter-form button {
    background: white;
    color: var(--primary-color);
    border: none;
    padding: 1rem 2rem;
    border-radius: 0.5rem;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s ease;
}

.newsletter-form button:hover {
    background: var(--bg-secondary);
    transform: translateY(-2px);
}

/* Footer */
.footer {
    background: var(--text-primary);
    color: white;
    padding: 3rem 0 1rem;
}

.footer-content {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 2rem;
    margin-bottom: 2rem;
}

.footer-section h3,
.footer-section h4 {
    margin-bottom: 1rem;
    font-weight: 600;
}

.footer-section ul {
    list-style: none;
}

.footer-section ul li {
    margin-bottom: 0.5rem;
}

.footer-section a {
    color: #cbd5e1;
    text-decoration: none;
    transition: color 0.3s ease;
}

.footer-section a:hover {
    color: white;
}

.footer-bottom {
    text-align: center;
    padding-top: 2rem;
    border-top: 1px solid #374151;
    color: #9ca3af;
}

/* Responsive Design */
@media (max-width: 768px) {
    .nav-menu {
        display: none;
    }

    .hamburger {
        display: flex;
    }

    .hero-content {
        grid-template-columns: 1fr;
        text-align: center;
        gap: 2rem;
    }

    .hero-title {
        font-size: 2.5rem;
    }

    .hero-buttons {
        justify-content: center;
        flex-wrap: wrap;
    }

    .about-content {
        grid-template-columns: 1fr;
        gap: 2rem;
    }

    .contact-content {
        grid-template-columns: 1fr;
        gap: 2rem;
    }

    .newsletter-form {
        flex-direction: column;
    }

    .section-title {
        font-size: 2rem;
    }
}

@media (max-width: 480px) {
    .hero {
        padding: 5rem 1rem 2rem;
    }

    .hero-title {
        font-size: 2rem;
    }

    .nav {
        padding: 1rem;
    }

    .container {
        padding: 0 1rem;
    }

    .research-card,
    .team-member,
    .publication-item {
        padding: 1.5rem;
    }
}

/* Smooth scrolling */
html {
    scroll-behavior: smooth;
}

/* Loading animation for page load */
@keyframes fadeInUp {
    from {
        opacity: 0;
        transform: translateY(30px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

.fade-in-up {
    animation: fadeInUp 0.6s ease-out;
}